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Like Bala, it would, therefore, be possible to produce coke or heroin on demand in our kitchen or garage. Insulin for people with diabetes and several pharma drugs and chemicals are under production through genetically modified E.It’s not possible to explain meditation to such a person through words, it has to be experienced, but drugs to a certain extent help a person get a hallucinatory experience of meditation.In order to prevent misuse of drug producing bacterial strains, developing and implementing a flexible and proportionate regulatory approach is a major challenge which will have to be addressed in our country.moistens the throats parched by the weed.Bala reaches out for his homebrew fermenter where the yeast cells cloned with the opium genes have been busy since several hours converting the sugar in the culture to morphine.For instance, if a contractor in Africa placed an order for it took about 18 months to get the drug.The scenario painted in the preceding stanza is not a figment of my imagination, John Dueber and his colleagues at University of California in Berkeley in 2015 succeeded in producing a genetically modified yeast which can feed on gluغير مجاز مي باشدe and produce morphine from which heroin can be derived.But, in the end, it’s only meditation that can give one the real experience, the experience one gets from the drug is just a hallucination, a dream-like sensation which is very similar.coli-cloned Claviceps enzyme and enzyme-free glutathione to convert the intermediate into agroclavine in vitro. With synthetic biology we wouldn’t need crops to grow drugs, we would be able to produce them in the labs or our homes. Much of the morphine so produced has undergone acetylation to heroin, and the fermenter at the press of a button is ready to belch out the home-brewed heroin.” An engineered strain of yeast can now produce the drug on demand and is “head and shoulders above the plant” at making it, says Jack Newman, co-founder and senior adviser at Amyris, a microbial engineering company. Jayanth Murali, an IPS officer, is director DVAC, Chennai. Bala presses the button, the ritual gets repeated, the dragon gets chased all over again. The ergot fungi called Claviceps purpurea produces fruiting bodies which are the source of the lysergic acid.At long last, I believe, that attraction of man to drugs is mostly spiritual.The contemporary industrial method of lysergic acid production, in which decaying matter fuels fermentations of Claviceps is cumbersome with extremely low yields.Yeast or bacteria, on the other hand, are advantageous too as they are easy to conceal, grow and transport.

Fifteen cronies who have known each other since school have bunched-up for a party at a beach house off the ECR road, Bala their favourite Psychonaut host, plucks at a bag of heroin, and sets forth, to cut it into lines at the table.3 per base pair, it’s now well within reach of each and everyone. Firstly, there won’t be any need for cultivating thousands of acres of land to grow cocaine, LSD or pot. LSD was first made by Albert Hofmann in 1938 from lysergic acid, from a fungus called ergot. Efforts would also have to be taken to keep drug-producing bacterial strains in controlled environments that are licensed by regulators and make it a mandatory requirement for all such strains to contain a marker, such as a DNA watermark, that would make them identifiable to law-enforcement agencies. He is unaware that the connection he is yearning for is possible from prayer, meditation and other spiritual practices.Their findings, published in Nature Chemical Biology, has opened the doors for yeast-derived “home-brewed” cheap and easy illegal drugs.coli, etc.As the غير مجاز مي باشدt of synthesising DNA has drastically declined over the last 20 years and is now around $US0. Studies are in the pipeline at other institutes to see how fast-growing Streptomyces bacteria strains can be exploited for producing cannabinoids, insinuating a potential new method of generating the compound without cultivating marijuana. Its mass production became a possibility mainly due to the efforts of Jay Keasling and colleagues at the University of California, Berkeley, who transferred the artemisinin genes into a yeast cell.Other cronies string along batteries manufacturers with the ritual, take turns to snort and sniff the lines, getting their minds blown away to ecstatic existential realms. Last, of all, meditation is hard and requires consistent and committed practice, but drugs, on the other hand, are easy but they promise only a fleeting taste of instant transient sensory cum spiritual gratification, not the actual unalloyed eternal bliss of spiritual life which meditation offers. Similarly, Edwin Wintermute and Pam Silver at Harvard’s Department of Systems Biology are on the point of sneaking that crucial segment of Claviceps genome into baker’s yeast to get it to produce LSD.In a jiffy, they are all as high as kites feeling floaty and nice. Nothing now seems more urgent in this world than to claw one’s way back to regain that familiar euphoric high and to clasp and cling to it like an obsessed lover. Pharma firms, as a result, are unable to produce over and above 40,000 pounds of it every year. It stems from man’s dissatisfaction with his mundane existence.

What he is actually searching for is a deep spiritual connection, not drugs.Its production was scanty and erratic owing to the whimsicalities of growing sweet wormwood.But today we can pin our faith on efficient production after Matuschek et al in 2010 triumphed using an E.Dr K. They twirl around in the room, hold hands, sense unperceived compassion for another, laugh, marvel and feel goddamn lucky to be such wonderful friends. Prior to this, artemisinin production was tortoise-like because it took about a year for the crop of sweet wormwood to grow. Globally, more than 16 million people use opiates illegally.Cannabinoids like THC are utilised in pain remedy, but present-day methods of cultivating marijuana and extracting the active compounds not only غير مجاز مي باشدt a pretty penny but is also toilsome rendering minuscule yields.Similarly, by deploying synthetic biology researchers at Stanford are making genetically altered yeast to scoop out a non-narcotic cough suppressant known as noscapine, which is sourced naturally from opium poppies. Lastly, the traditional methods are unreliable as well as time-consuming, as the plants can be damaged by bad weather, pests and disease.Ten hours later, zonked out and exhausted from dancing, little by little the declining high seems to gradually give way to a grotesque melancholy - an inevitable crash stares at them, they can clearly sense the comedown, an achy, twitching sadness.coli and other microbe cells for decades now. Artemisinin isolated from the plant Artemisia annua, or sweet wormwood, is a herb employed in Chinese conventional medicine.There are several advantages for drug lords to produce drugs from genetically modified microbes. Albeit, the only drawback is that its productiveness would need to be increased a few hundred times before it becomes a popular way. He snorts a line of heroin and another of MDMA.Lysergic acid diethylamide (LSD), also known as acid, is a hallucinatory drug.One of the greatest success stories of synthetic biology has been the synthesis of artemisinin an antimalarial drug.There also won’t be any need to smuggle coke or heroin across borders. The bacteria with the cloned genes would express cocaine, heroin, morphine, pot, LSD etc. There is no ecstasy, there is no real joy.It is now technically feasible for anyone to concoct illegal drugs from the comfort of one’s home with a little access to yeast cells and some knowledge of fermentation.Analogously, in 2015, research workers at the Technical University of Dortmund released a study detailing their successes in genetically modifying a yeast cell to crank out the main active compound in ganja (Cannabis) called THC, which has been a fantasy of stoners for more than a decade.

There would be no fear of being detected by surveillance aircraft, no fear of drug-sniffing dogs or destruction of the crop by drug enforcement agencies. All said and done, decentralised and localised production would almost certainly reduce the غير مجاز مي باشدt and increase the availability of illegal opiates - substantially worsening a worldwide problem.There are now several commercial companies that provide DNA synthesis services, so the process can be easily outsourced: a customer can place an order for a DNA sequence on the net and synthesise a complete microorganism - using only published DNA sequence information and mail-ordered nucleotides. Drugs are also capable of helping a person gain insight into themselves, their lives, and the nature of the universe, which may eventually help a person, know the taste and feel of spiritual life.Once we have the DNA sequence of a gene or group of genes for a particular drug, we will be able to synthesise the gene and clone it into microbes such as yeast, E. Life seems so freaking amazing that nothing seems to matter. It was discovered in 1972 by Youyou Tu, a Chinese scientist, who was awarded half of the 2015 Nobel Prize in Medicine for her finding. Simultaneously, joints get lit and passed around, while the red wine which is being sipped . The concept of using microscopic organisms to make drugs is not new.Man does not know that the aching void inside of him is because of spiritual emptiness. Law-enforcement agencies would find it massively difficult to control the distribution and spread of an opiate-producing yeast strain. It’s man’s search for meaning and spiritual bliss which sometimes leads him to drugs and hallucinogens. The worldly existence of man is full of sorrow and suffering. Laws would have to be enacted to make possession, release and distribution of drug-producing bacterial strains illegal

When asked why lesser numbers of the next generation are taking over their family businesses, he quips, “Even my next generation isn’t too involved in the business. The profits at Amara Raja Batteries had tanked to 0,000 from . However, when I finally returned from the US, the odds were heavily stacked against entrepreneurs. We planned well, sensed the glitches and moved ahead. He reveals that at one point, he told his father, “This town isn’t big enough for the two of us and one has to quit. Jayadev’s grandfather was a freedom fighter while his mother was in politics for 25 years. How-ever, I am happy that they are following their dreams and passions.Passing the baton from one generation to the next proved to be even more difficult. I finally convinced him and Amaron batteries was launched in 2000. Galla, founder and chairman of Amara Raja Group discovered when he started off in 1985 in his home district of Chittoor in Andhra Pradesh.He shares, “For the first nine months of this fiscal year, we’ve run way ahead of our earlier pace. That’s why it took me 22 years to take the first step into politics,” says Jayadev, a TDP LS member.” He adds, “The worries weren’t unjustified.

People have started to believe that I can carry forward my family business in the way my father used to. “The biggest lessons in life are those you learn from people around you, that you implement to benefit others. We rose like a phoenix,” he says proudly. We were going down with every quarter. “I felt disconnected from the people and culture and realised the need to live in India. I am following my interests too.Ramachandra and Jayadev Galla“When I took over, everyone thought that the business would be ruined, and my dad asked, ‘why did you get into this?’ But I was confident of getting us out of the morass. Now, my father says I can inspire people!”Just like his business, the decision to enter politics too was taken at a young age. “Legacy definitely mattered. I took aggressive steps famous car batteries and brought in new ideas,” recalls Jayadev, candidly admitting that it was difficult to work with his father. I felt that I could use my experience and knowledge to make a difference in India,” says Jayadev. When I moved back to India, I wanted to enter politics too. As Ramachandra N.”Ramachandra reasons, “The automotive battery foray needed expertise in branding and distribution, which we did not possess. This is a really proud moment for me.While originally, the business focused only on batteries used by the telecom, power and oil-and-gas sectors, Jayadev wanted to expand into vehicles which were dominated then by Exide industries. It’s only after you have lived as a citizen, contributed and achieved something for the people of this country, that you can enter politics. We were established but also had to go to the next level. I am happy that I finally gained my father’s trust, and he admits I took aggressive steps and brought in new ideas. It was a huge company which he had created after years of hard work and dedication.“But the overall economy when I entered the business was weak.

The growth wasn’t without conflict between the two generations. “We worked hard and started to innovate and from that low point on, our revenues grew 18-fold. “The dynamics of the economy were changing rapidly. He took over the business from Galla senior in 2003, by when Amara Raja had already come a long way. But like all other things, one needs to have the right skills.The early ’80s in India weren’t an easy time to do business.6 million the previous year.” Ramachandra took a backseat and Jayadev took over the full reins. Be it business or politics, one can’t move ahead alone. I worked very hard on convincing him and putting my ideas into action.”Despite the apprehensions, Jayadev was confident that they’d be able to pull themselves out of the crisis. While ensuring that the business grew and met all its targets, I also had the responsibility of ensuring that my father’s vision for the company remained our guiding principle,” says Jayadev, admitting that the challenges faced by him and his father were different. Every person in the company began to think that I might ruin the whole business. Finally, after three years of constant arguments with my father, he relented and I got the opportunity to introduce my ideas,” says Jayadev. Issues like lack of infrastructure, logistics, and non-availability of skilled labour made it an uphill task,” says Ramachandra. At the same time, there were expectations and little options for failure.”. Initially, my father was apprehensive if I could do justice to our business or not. But my father resisted, because the sector had an entrenched player like Exide on one end and unorganised players churning out cheap knockoffs on the other. My sons — Ashok and Siddharth — are interested in movies.”“It took five years to convince him. The government at that time was supporting non-resident Indians for entrepreneurship to take the country’s industrial growth forward. My father too had some loss of faith in my capabilities. Timing played a key role as the industrial battery prices had crashed, the auto segment that we forayed into didn’t take off, and the overall economy was weak. “I pushed for auto batteries because being only in industrial mode made the company vulnerable. I wanted to be in politics and am balancing my commitment as a politician and life as a businessperson. His son, Jayadev (Jay) Galla’s (Vice-Chairman and Managing Director, Amara Raja Batteries) entrepreneurial journey began in America

Bajaj Dominar 400 - (Rs 1. The motorcycle gets a 373.1.6 Nm @ 8000 rpm. We have listed out five affordable motorcycles that offer ABS. The front wheel is equipped with a 270mm petal-type disc rotor and the rear is equipped with a 200mm petal-type disc rotor. Front disc size is 320mm and rear disc size is 230 mm. Sharp design, raw power and affordability are the bike&wholesale GEL batteries39;s forte that no bike has managed to challenge yet.96 lakh, ex-showroom, Delhi)It is the most # modern bike of the lot.The motorcycle is built around a steel trellis frame and gets WP USD forks at the front and WP monoshock unit at the rear.34 lakh, ex-showroom, Delhi)The first full-faired motorcycle from Bajaj also became the first ABS equipped motorcycle from the company. TVS Apache RTR 180 - (Rs 80,319, ex-showroom, Delhi)It was the first most affordable motorcycle which was launched with ABS in the country. It is the first motorcycle in its segment to get all LED headlamps.5 Nm @ 6500rpm.com. The motorcycle is powered by a 373. The bike is available in Midnight Blue, Twilight Plum and Moon White colour options.26 lakh, ex-showroom, Delhi)The KTM RC 390 is unarguably the most feature laden fully faired motorcycle available in the country for the price it commands.5PS @ 9000rpm and a peak torque of 35Nm @ 7000rpm mated to a six-speed gearbox.

It needs more than a غير مجاز مي باشدmetic update now. It is a very important safety feature that reduces the possibility of a crash. Bike makers have started offering ABS on entry-level motorcycles, and moreover, the Indian government has also made ABS mandatory on all two-wheelers above 125cc from 2018 onward. The bike is available in White, Black and Matt Gray colour options.Anti-Lock Braking system, generally known as ABS, prevents the wheels from locking and tyres from skidding in the case of emergency braking. Source: Zigwheels. The 390 Duke is constructed around a steel trellis chassis.3cc engine which develops 35PS @ 8000rpm and a peak torque of 35Nm @ 6000rpm.The Apache RTR 180 gets a Double Cradle SynchroStiff chassis. The RC 390 is available in a single Black & White colour option with orange painted wheels and chassis. KTM RC 390 - (Rs 2. It was also the first performance entry level naked motorcycle which was equipped with dual channel ABS as standard.4.53 lakh, ex-showroom, Delhi)The Dominar 400, Bajaj’s flagship motorcycle, is loaded with features that most of the bikes in its competition miss out on. Front disc size is 300mm and rear disc size is 230mm.2. The company has recently updated the motorcycle with new colours and graphics, christening the motorcycle laser edged edition, which surely add more flavour to the motorcycle. Bajaj Pulsar RS200 - (Rs 1. The bike also comes with TVS’s RLP (Rear Wheel Lift-off protection). A specially interesting feature of this motorcycle is that the ABS system can also be completely switched off.3cc engine which develops 43.3. The Apache RTR 180 is shod with a 90/90 R17 tyre at the front and a 110/80 R17 tyre at the rear. It gets 320mm discs at the front and 230mm disc at the rear with dual channel ABS offered as standard. It gets dual channel ABS offered as an optional extra and the prices are different for that model. The bike gets dual channel ABS (ABS for both the wheels) as an option. It now gets a bigger front disc of 320mm, compared to the model it replaces, and 230mm rear disc.

It is powered with a 177. The Dominar 400 is powered by a 373. KTM recently launched the motorcycle with an all new TFT screen. It is the most affordable motorcycle with ABS.5cc engine which develops 24. 5.3cc engine that develops 45PS @ 8000rpm and a peak torque of 36Nm @ 6000rpm. The Pulsar RS200 gets a single channel ABS system (only for the front wheel) which is offered as standard. KTM 390 Duke – (Rs 1. Though it comes with all the bells and whistles offered on modern day motorcycles, the RTR 180 now feels dated. It is offered in Orange colour.3 PS @ 8500 rpm and a peak torque of 15.4cc engine which develops 17.5 PS @ 9750 rpm and peak torque of 18. It is powered by a 199. It is offered in two colours – Graphite Black and Racing Blue

When a battery is charging, lithium ions are extracted from the positive electrode and move through the crystal structure and electrolyte to the negative electrode, where they are stored..“The oxygen pillars, or shear planes, make these materials more rigid than other battery compounds, so that, plus their open structures means that more lithium ions can move through them, and far more quickly,” Griffith said. Griffith suggests that the structural complexity and mixed-metal composition are the very reasons the materials exhibit unique transport properties.However, when charged wholesale batteries factory at high rates, it tends to form spindly lithium metal fibres known as dendrites, which can create a short-circuit and cause the batteries to catch fire and possibly explode.

Most negative electrodes in current lithium-ion batteries are made of graphite, which has a high energy density. The faster this process occurs, the faster the battery can be charged, researchers said.Scientists have identified a new class of materials which could be used to make smartphone batteries that charge faster. The researchers, from the University of Cambridge in the UK, used materials with a complex crystalline structure and found that lithium ions move through them at rates that far exceed those of typical electrode materials, which equates to a much faster-charging battery. Using a technique called pulsed field gradient (PFG) nuclear magnetic resonance (NMR) spectroscopy, which is not readily applied to battery electrode materials, the researchers measured the movement of lithium ions through the oxides and found that they moved at rates several orders of magnitude higher than typical electrode materials.The niobium tungsten oxides used in the current work have a rigid, open structure that does not trap the inserted lithium and have larger particle sizes than many other electrode materials.“We are always looking for materials with high-rate battery performance, which would result in a much faster charge and could also deliver high power output,” said Kent Griffith, a postdoctoral researcher in Cambridge’s Department of Chemistry. Additionally, their physical structure and chemical behaviour give researchers a valuable insight into how a safe, super-fast charging battery could be constructed, and suggest that the solution to next-generation batteries may come from unconventional materials.

The oxides are held open by ‘pillars’ of oxygen, which enables lithium ions to move through them in three dimensions. “In high-rate applications, safety is a bigger concern than under any other operating circumstances,” said Professor Clare Grey, also from the Department of Chemistry at Cambridge. In their simplest form, batteries are made of three components: a positive electrode, a negative electrode and an electrolyte.Although these materials, known as niobium tungsten oxides, do not result in higher energy densities when used under typical cycling rates, they come into their own for fast charging applications, according to the research published in the journal Nature. “These materials, and potentially others like them, would definitely be worth looking at for fast-charging applications where you need a safer alternative to graphite,” Grey said. “Many battery materials are based on the same two or three crystal structures, but these niobium tungsten oxides are fundamentally different,” said Griffith

Their aspirations, dreams and fears are just like anyone else’s. They too feel shy when a boy compliments them. She can stand the strange looks and harsh comments people throw at her but not everyone, who has been through that trauma, is that strong..”Breathing freedomIn the course of the project, Niraj realised that all the girls had just wanted to feel normal.It’s said that a picture is worth a thousand words but each photograph clicked by Niraj Gera tells a huge غير مجاز مي باشدa of grit and determination. They suffer from acute depression and suicidal tendencies. In fact, beauty is a relative term. “I had gone to the protest just to click few snaps. “None of them wants to be identified as a victim or a survivor.”Untainted loveBut his bigger battle was to convince the survivors how beautiful they are. Also, all the girls were from different cities and I had to travel a lot to do the shoots. So, my series also aims to sensitise their families,” he says.

He conducted a week-long workshop with the survivors where he taught them about spirituality, meditation and breathing techniques, which he says helped in killing the anxiety and self-doubt. You will be shocked to know that some of their families haven’t accepted them. Talking about why it took so long, he says, “I am a businessman too, so I had other commitments as well. I took up the project not just as a photographer but also as an activist.Longing for the pastNiraj has shown the series to his guru Sri Sri Ravi Shankar and he has asked him to bring the girls to the ashram. If the emotion didn’t express the transformation, it didn’t work for me and the shoot had to be done again. His upcoming exhibition titled “Sacred Transformations” will showcase images of women acid attack survivors and chronicle their emotional journey. They want no special treatments.

It was important for them to understand that before changing the world, they had to change themselves,” says Niraj who is also an Art of Living teacher. He continues, “I want to sensitise people that women are not objects and outer beauty is not everything. The lensman is also getting a lot of good feedback from all around as he has been approached by social workers wanting to lend a helping hand to the noble cause.In the series of 36 photographs, which will be exhibited at Arpana Caur Gallery from Monday, Delhi-based Niraj has attempted to communicate the plight of the survivors and the idea of doing so, struck him when he went to a protest march in 2014 where he saw them asking for basic rights. Over the years, they all have become like my family members,” says the 40-year-old.The unrobable joyThe whole series took about 28 months to complete.

“Someone like Laxmi, who is also the face of the acid attack campaign — “Stop Acid Attacks”, is a strong woman. There I saw the survivors asking for basic rights like job opportunities and ban of sale of acid. When someone treats them badly, their morale goes down. “I am going to keep a register at the exhibition and ask people to donate — not money but their skills to help the survivors become a part of the mainstream society,” he says before famous car batteries signing off. Lastly, most of the times, I was just not happy with the shot. I was so moved by their stories that I began to feel for their cause

But there is one laggard inside your phone. We will reserve a full throated 'three cheers' till batteries become as clever at their job, as the phone itself. Phones which run on Qualcomm's Snapdragon processor can deploy that company's Quick Charge technology, now into version 3.With no radical new battery technology in sight, the best the industry can offer us is one of two options: bigger batteries or a faster way to charge.

IBM made headlines last year suggesting one could replace the heavy carbon rod with air, except that the normal air we breathe is just not pure enough.Batteries remain the top pain point of phone owners, but some relief is coming.. She is now a student at Harvard and no one knows if she was able to commercially market her brainchild.0, which promises to charge the phone 3 times faster than with a normal charger. The Asus Zenfone Max which we reviewed on this page, has a 5000mAh battery and power saving circuitry that controls processor performance as well as screen brightness to assure at least 2 days on a charge.

These days the bigger battery brigade has gone way beyond the typical 2000mAh - 3000mAh of a year ago: By month end Xiaomi will be launching the Mi Max with a jumbo 4850mAh battery that promises to keep you going for 2 days between recharges, not bad considering this 6. Dr Gordon Moore had predicted, 50 years ago, that the performance of a semiconductor chip doubles every 18 months.5 device is more phablet than phone. These days the battery in a 5 or 6 inch handset with fairly typical multimedia uغير مجاز مي باشدe won't last the working day.

Three years ago Eesha Khare, an Indian-origin student in the US took a top prized at the Intel Science Fair with her invention, a Super Capacitor that could charge an existing phone battery in 30 seconds. At Loughborough University, they are working on fuel cells using hydrogen, which theoretically should power a phone for a week. In other words, feed and fatten the Li-ion -- or twist his tail to wake him up faster. The Gionee M5 Plus sports a 5020mAh battery and claims 47 hours of talk time and 12 hours of video wholesale car battery suppliers playback.There's plenty of talk of new and alternative materials -- but mostly they remain just that: talk. The Le Max 2 which was reviewed earlier has a 3100mAh battery backed by proprietary technology for a very short charge cycle.

It is the battery that fuels your phone -- and a pretty lousy job it has been doing -- till now.Another school of thought believes it is better to accelerate the recharge cycle than beefing up the battery size (which will inevitably make the phone bulkier). We may greet these stop gap solutions -- beefed-up on board batteries or reduced charge cycles -- with muted applause. And at this year's Mobile World Congress, Oppo unveiled what it called Super VOOC Flash Charge, which charges a 2500mAh battery in 15 minutes. And consider the technology: it has always been Lithium Ion for as long as we remember: very similar to the Leclanche cell we studied in school -- but with a compound of Lithium as the positive electrode, carbon or graphite as the negative pole and a salt of Lithium as the semi fluid in between, to drive the electric current.

The recently launched One Plus 3 phone offers its own patented Dash Charge technology with its 3000mAh and claims to offer one day's normal uغير مجاز مي باشدe with 30 minutes of charging.Remember the simpler times when your phone did just calls and text mesغير مجاز مي باشدes Once charged the device was good to go for ne week.Someone has calculated that mobile phone capability seems to mimic Moore's Law. So it seems, does the power under the hood of your hand phone, with today's octa-core processor, an eight-fold improvement in 5 years